WebApr 15, 2024 · 8625 353rd Ave NE , Carnation, WA 98014-6874 is a single-family home listed for-sale at $1,699,000. The 4,240 sq. ft. home is a 4 bed, 4.0 bath property. View more property details, sales history and … WebPotent, selective ATP-competitive GSK3 inhibitor. CAS Number: 556813-39-9. Purity: > 98%. Soluble in DMSO to 5 mM. Form / State: Solid. Source: Synthetic.
CHIR-98014 GSK-3 阻害剤 MedChemExpress
WebCHIR-98014 (CT98014) is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2. BIO WebCHIR 98014 is a glycogen synthase kinase-3 (GSK-3) inhibitor with IC 50 values of 0.65 nM and 0.58 nM for GSK3α and GSK3β, respectively. CHIR98014 is 500-fold to >10,000 … henry ford optimeyes shelby
CHIR-98014 ≥99%(HPLC) GSK-3 inhibitor AdooQ®
WebBromo- and extra-terminal domain inhibitors (BETi) have exhibited therapeutic activities in many cancers. However, the mechanisms controlling BETi response and resistance are not well understood. We conducted genome-wide loss-of-function CRISPR screens using BETi-treated KMT2A-rearranged (KMT2A-r) c … WebCHIR98014, also known as CT-98014, is a reversible, cell-permeable inhibitor of GSK3α and GSK3β (IC50 = 0.65 and 0.58 nM, respectively). It is inactive against a series of other serine/threonine or tyrosine kinases. ... CHIR-98014 is a potent, cell-permeable GSK-3 inhibitor with IC50s of 0.65 and 0.58 nM for GSK-3α and GSK-3β, respectively; it WebAug 1, 2024 · A significant reduction in cell viability was observed after treatment with 1 μM of CHIR 98014 and BIO for 72 h. e BrdU assay of 10 μM BIO and CHIR 98014-treated H1975 cells demonstrated ... henry ford optimeyes in west bloomfield mi