Camptosar irinotecan package insert
WebSep 26, 2024 · Camptosar Dosage Generic name: IRINOTECAN HYDROCHLORIDE 20mg in 1mL Dosage form: injection, solution Drug class: Miscellaneous antineoplastics Medically reviewed by Drugs.com. Last updated on Sep 26, 2024. Colorectal Cancer Combination Regimens 1 and 2 Administer CAMPTOSAR as a 90-minute intravenous … WebThe CAMPTOSAR (irinotecan) package insert recommends a reduced initial dose be considered for patients homozygous for the UGT1A1*28 allele and are at an increased risk for neutropenia following initiation of CAMPTOSAR treatment. AutoGenomics Doc EM-34028E (English) Rev. G Page (CO 2307) October 2012
Camptosar irinotecan package insert
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WebTrade Name: CAMPTOSAR; CAMPTO Chemical Family: Mixture Intended Use: Pharmaceutical product used as Antineoplastic 2. HAZARDS IDENTIFICATION ... Irinotecan Hydrochloride 100286-90-6 Not Listed Mut. Cat.3;R68 Repr. Cat.3;R61 Xn;R22 2% Sodium hydroxide 1310-73-2 215-185-5 C;R35 ** WebActive ingredient: irinotecan hydrochloride trihydrate. The concentrate contains 20 mg/ml irinotecan hydrochloride trihydrate (equivalent to 17.33 mg/ml irinotecan). Excipients: sorbitol, lactic acid and water for injections. The pH of the solution is adjusted to 3.5 with sodium hydroxide.
WebFeb 4, 2024 · Irinotecan is given by intravenous (IV, into a vein) infusion. It is used in a variety of chemotherapy regimens. The actual dose and dosing schedule will depend on your treatment regimen, body size, and general health. You may receive anti-nausea medication and anti-diarrheal medication like atropine prior to the irinotecan infusion. WebIrinotecan hydrochloride (HCL) is an antineoplastic drug that is a semisynthetic derivative of camptothecin, an alkaloid extract from plants. The drug works by causing strand breaks in DNA that the cell cannot repair leading to cell death. Irinotecan is FDA approved for the following indications:
WebAug 1, 1998 · ABSTRACT: Irinotecan (CPT-11 [Camptosar]) is an important new chemotherapeutic drug that demonstrates activity against a broad spectrum of malignancies, including carcinomas of the colon, stomach, and lung. ... Pharmacia & Upjohn: Irinotecan Package Insert. 59. Goncalves E, de Costa L, Abigerges D, et al: A new enkephalinase … WebCamptosar (irinotecan) dosing, indications, interactions, adverse effects, and more Drugs & Diseases irinotecan (Rx) Brand and Other Names: Camptosar Classes: Antineoplastics, Topoisomerase...
WebIrinotecan (Camptosar) patient drug information (UpToDate) History of changes in FDA indication 6/14/1996: Initial accelerated approval for the treatment of patients with metastatic carcinoma of the colon or rectum whose disease has recurred or progressed following 5 …
WebIrinotecan (Camptosar) patient drug information (UpToDate) [4] History of changes in FDA indication 6/14/1996: Initial accelerated approval for the treatment of patients with metastatic carcinoma of the colon or rectum whose disease has recurred or progressed following 5 … highkey earbudsWebMay 11, 2024 · CAMPTOSAR is indicated for patients with metastatic carcinoma of the colon or rectum whose disease has recurred or progressed following initial fluorouracil-based therapy. 2 DOSAGE AND ADMINISTRATION 2.1 Colorectal Cancer Combination Regimens 1 and 2 Administer CAMPTOSAR as a 90-minute intravenous infusion … how is a self defense stick helpfulWeb1 Camptosar® 2 irinotecan hydrochloride injection 3 4 For Intravenous Use Only 5 WARNINGS 6 CAMPTOSAR Injection should be administered only under the supervision of a 7 physician who is experienced in the use of cancer chemotherapeutic agents. Appropriate 8 management of complications is possible only when adequate diagnostic and treatment highkey double chocolate brownieWebView Fresenius Kabi's Oncology Product Portfolio including Irinotecan Hydrochloride Injection – cross references to branded drug Camptosar®. ... Cross references to branded drug Camptosar ® 100 mg per 5 mL Order. Package Insert Download NDC No. 63323-193-55 Product No 109355 Description SD Amber Vial ... highkeyfxWebMar 21, 2024 · Irinotecan (Camptosar ©, CPT-11), a topoisomerase I inhibitor, is a commonly used cytotoxic chemotherapeutic in the treatment of multiple malignancies, particularly of gastrointestinal origin. Dysarthria secondary to irinotecan has been described as a rare side effect in a few case reports with limited data to recommend appropriate … high key fotografie tipsWebThe concentrate contains 20 mg/ml irinotecan hydrochloride trihydrate (equivalent to 17.33 mg/ml irinotecan). Excipients: sorbitol, lactic acid and water for injections. The pH of the solution is adjusted to 3.5 with sodium hydroxide. Vials of CAMPTO contain 40 mg or 100 mg or 300 mg of irinotecan hydrochloride trihydrate. THERAPEUTIC INDICATIONS high key fotografie landschaftWebMar 18, 2009 · Camptosar (irinotecan) package insert. Japan: Yakult Honsha Co, LTD and Daiichi Pharmaceutical Co, LTD; 2007. 20. Saltz LB, Cox JV, Blanke C, et al. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. NEJM. 2000;343:905-914. 21. Saltz LB, Niedzwiecki D, Hollis D, et al. Irinotecan fluorouracil … high key editing in photography